11^th World Congress on Human Genetics and Genetic Diseases July 10-11, 2023 Dubai, UAE

Track 1: Classical Genetics

The methods and techniques of genetics that were in use before to the development of molecular biology are referred to as "classical genetics." Genetic linkage was a crucial finding of classical genetics in eukaryotes. Mendelian inheritance's rules were broken when it was discovered that some genes do not segregate independently during meiosis. This discovery also gave science a technique to map traits to specific chromosomal locations. Even today, linkage maps are widely employed, particularly in plant breeding. Classical genetics is the area of genetics that only considers the visible signs of reproduction. The experiments on Mendelian inheritance by Gregor Mendel, who made it possible to discover the fundamental mechanisms of heredity, make it the oldest field in genetics.

• Allele
• Phenotype
• Genomics
• Linkage maps
• Mutation

Track 2: Immunogenetics

In order to study inherited factors that affect immunity, intraspecific heterogeneity, tissue receptor inheritance, genetic and population dimensions of host-microbe interactions, and tissue incompatibility, the field of biology known as immunogenetics combines immunology, molecular biology, and genetics. The area of medical genetics and immunology known as "immunogenetics" or "immungenetics" studies how the immune system and genetics are related. Type 1 diabetes and other autoimmune illnesses are complicated genetic features brought on by immune system flaws.

• Major Histocompatibility Complex.
• Human Leukocyte Antigen
• Vaccine Efficacy
• Mono-specific Antibody

Track 3: Phylogenetics

Phylogenetics is a potent method for determining how modern species have evolved. Scientists can explain the similarities and differences between species and learn more about how species have developed by looking at phylogenetic trees. Numerous medical and biological disciplines use phylogenetics, such as forensic science, conservation biology, epidemiology, drug discovery, drug design, protein structure and function prediction, and gene function prediction.

Track 4: Comparative Genomics

In order to better understand how species arose and to discover the function of genes and noncoding areas in genomes, comparative genomics compares the entire genetic makeup of two organisms directly.

Comparative genomics provides fresh insight into genome evolution and the way natural selection shapes DNA sequence evolution by analysing genome sequences from various species.Softwares in trend for comparitive genomics are :

• Easyfig
• Ensembl
• KEGG

Track 5: Clinical Genetics

Clinical genetics is a branch of medicine that offers genetic counseling and diagnostic services to people or families who have or may develop illnesses that have a genetic foundation. Genetic disorders can affect every body system in any age group. The goal of genetic services is to assist people who have or are at risk for genetic disorders in living and reproducing as normally as possible.

Track 6: Gene Function Prediction& Genome Annotation

The approaches for predicting gene function, which automatically annotate genes with information about their functions by utilizing available resources, can be broadly categorized into experimental data-based methods and knowledge-based methods. First, a lot of techniques based on experimental data were applied.

Protein-coding genes, as well as other functional genome units like structural RNAs, tRNAs, short RNAs, pseudogenes, regulatory areas, direct and inverted repeats, insertion sequences, transposons, and other mobile elements, are predicted as part of the  multi-level process of genome annotation level process of genome annotation.

• GENEID
• JIGSAW
• AUGUSTUS
• EuGene

Track 7: Genome Integrity

The Genome Integrity Unit focuses on cancer and early development with particular interest in how cells retain the health of their DNA. Cells respond to DNA damage by using a precise DNA repair process to preserve genomic integrity.

Track 8: Genetic Epidemiology

With conceptual and methodological input from epidemiology, genetic epidemiology initially grew out of population genetics, specifically human quantitative genetics. It is relatively recent field of study, aims to clarify how genetic and environmental variables interact to cause disease in populations.

Four main types of research study designs are used to conduct the tests of analytical epidemiology;

• Cross-sectional studies
• Case-control studies
• Cohort studies
• Controlled clinical trials

Track 9: Common Genetic Diseases

Regardless of time zone and latitude, there are some genetic faults that occur most frequently worldwide for a variety of reasons, leading to prevalent or common genetic diseases.More research is being conducted and advances are noting every day.

• Down syndrome (Trisomy 21)
• Fragile X syndrome
• Klinefelter syndrome
• Triple-X syndrome
• Turner syndrome
• Trisomy 18
• Trisomy 13

Track 10: Lethal Genetic Diseases

Fatal alleles, often known as lethal genes or lethal, are alleles that result in the demise of the carrying organism. They frequently occur from mutations in genes that are crucial for development or growth. Depending on the gene or genes involved, lethal alleles might be recessive, dominant, or conditional. Lethal alleles can kill an organism before or after birth, however, they typically show up early in development.

• Cystic fibrosis
• Sickle-cell anemia
• Achondroplasia

Track 11: Nutrigenetics & Nutrigenomics

Our understanding of the processes by which nutrition impacts the metabolic pathways underlying homeostatic control has increased thanks to nutrigenomics. This can then be used to identify naturally existing chemical components in food that may delay the onset of diseases including cancer, type-2 diabetes, and obesity.  Based on genetics, nutrigenetics studies how your body reacts to foods.

Track 12: Cancer Genetics

The field of science, cancer genetics focuses on identifying the genes and metabolic processes that promote the growth of cancer. In addition, networks and pathways that contribute to tumor growth as well as the interactions between cancer genes that support tumor evolution are of concern to cancer genetics.

Track 13: Gene Therapy

Gene therapy is a medical strategy that addresses the underlying genetic issue in order to treat or prevent disease. Instead of utilizing drugs or surgery, gene therapy procedures allow doctors to treat a problem by changing a person's genetic composition.

Ex vivo, in vivo, and in situ gene therapy are the three main subtypes. Ex vivo gene therapy involves removing the patient's affected cells and modifying them genetically. In vitro gene therapy is another name for this sort of treatment, which is especially useful for blood illnesses. There is one last gene therapy plan in which the viral vector is given directly to the patient.

• Germline therapy
• Somatic gene therapy

Track 14: Neurogenetics

Neurogenetics is the study of how heredity affects how the nervous system develops and works. It is based mostly on the observation that individuals' neurological systems, even those of the same species, may not be identical, and views neural features as phenotypes (i.e., manifestations, measurable or not, of an individual's genetic make-up). As its name suggests, it incorporates elements from both genetics and neurology research, concentrating on how an organism's genetic makeup influences the traits that are manifested in that creature. Variations in this DNA sequence can affect a person's quality of life in a variety of ways. Neurogenetics is investigated in relation to neurological disorders, behaviour, and personality.

Research in neurogenetics advances knowledge of the genetic underpinnings of both normal and pathological nervous system function. efforts to comprehend the genetic basis of brain problems.

Methods used for analysis;

• Clinical exome sequencing
• Transgenic RNAi

Track 15: Pharmacogenomics

Pharmacogenomics, also known as pharmacogenetics, is the branch of science that looks at how a person's genes influence how they react to pharmaceuticals. Its long-term objective is to assist physicians in choosing the medications and dosages that are ideal for each patient. Each year, severe medication responses lead to more than 120,000 hospitalizations, according to estimates. By locating people who are at danger, pharmacogenomics may be able to stop these. The effectiveness and expense of healthcare may both increase. Pharmacogenomics may make it easier to find the right drugs and dosages.

Track 16: Genetics Cardiovascular Diseases

A broad category of relatively uncommon heart illnesses are included by the term "inherited cardiac conditions" (ICC). The term "genetic cardiac conditions" is also used to describe them. ICCs are brought on by a flaw, or mutation, in one or more of our genes. Heart failure symptoms may be caused by inherited genetic abnormalities that alter the structure of the heart muscle. The electrical system of the heart can be impacted by gene abnormalities as well, which may result in irregular cardiac rhythms.

• Hypertrophic Cardiomyopathy (HCM) idiopathic
• Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Track 17: Population Genetics

The study of genetic diversity within and between populations, as well as the evolutionary processes that account for this variation, is known as population genetics. It is based on the Hardy-Weinberg law, which holds true as long as there is a sizable population, random mating, and minimal mutation, selection, and migration.

Tools (software) used for population genetics analysis

• NE ESTIMATOR
• BOTTLENECK
• LAMARC

Track 18: Biochemical Genetics

Biochemical genetics combines genetics with biochemistry. The structure and function of cellular components, including proteins, carbohydrates, lipids, nucleic acids, and other biomolecules, as well as their roles and transformations during life processes, are a major focus of biochemistry. Clinicians must have a fundamental understanding of the benefits and drawbacks of biochemical testing in order to interpret test results, decide when to visit a specialist, or explain results to patients.

Track 19: Genetic Medicine

The area of medicine known as medical genetics deals with the diagnosis and treatment of hereditary diseases. Human genetics is a branch of science that may or may not have applications in medicine, whereas medical genetics refers to the use of genetics in the delivery of medical treatment. Research on the causes and transmission of genetic illnesses, for instance, would fall within the scope of both human genetics and medical genetics, whereas the diagnosis, treatment, and counselling of those who have genetic abnormalities would fall under the purview of medical genetics.

Track 20: Genetic counseling

You can learn more about genetic diseases and how they might impact you or your family through genetic counseling. Your personal and family health history will be gathered by the genetic counselor or other healthcare provider. They can use this data to assess the likelihood that you or a member of your family has a genetic disorder.

• Estimating risk for certain conditions
• Genetic testing throughout pregnancy
• Pregnancy support services

Track 21: Yoga practice and genetic changes

The basic genetic blueprint for all living things is found in DNA. Recent research demonstrates that yoga not only has the advantages like, but also profoundly affects how genes work. This results from non-genetic effects and is referred to as an epigenetic effect.

• Molecular level changes in gene
• Mental health development.

Only the study of traits, their properties, and outcomes constitutes the study of heritable traits. These include nuclear hereditary traits, developmental hereditary qualities, people hereditary qualities, quantitative hereditary qualities, and human hereditary qualities. It integrates the study of value formulation, quality design, change assessment, cytogenetic and genomic imaging, genome construction and affiliation, inherited and actual planning, disease association considers nuclear diagnostics, hereditary characteristics of mind-boggling illnesses, epistatic collaborative efforts, and various thoughts. Additionally, it selects particular genetic components that cause diseases. It offers a variety of focal points, such as the detection, assurance, and treatment of many illnesses, including risky development, cardiovascular conditions, and other hereditary diseases.

According to estimates, the global market for digital pathology will expand from $5.9 billion in 2022 to $10.7 billion in 2027, at a compound annual growth rate (CAGR) of 12.5%.

Report scope:

North America, Europe, Asia-Pacific, and the Rest of the World are the four major geographic regions for which the digital pathology and telepathology market has been examined.

This will provide information about the standard operating procedure for pathology laboratories, however it will expressly not cover market research for standard path-lab equipment (e.g., conventional microscopes, slides). The report's discussion of connectivity and network difficulties will only apply to data and information generated by pathology labs and that relates to specific diagnoses; it will not address general hospital-based mHealth issues. Only diagnostic, research and development (R&D), and education and training uses of telepathology are considered in the report. It limits the application of telemedicine on a bigger scale.

Key Market Drivers

• Cost-Effectiveness Drives Expansion
• Rising Adoption of Digital Pathology to Enhance Lab Efficiency
• Increasing Incidence of Cancer

Target Group

Medical Research Laboratories

Academic Medical Institutes and Universities

Research and Development Companies

Genetics & Genomic Industries

Regional Analysis

According to advancements in diagnostics, restorative developments, and widespread application of new discoveries in innate characteristics, America is the best market for human genetic characteristics. Additionally, the market improvement is comparatively filled by the proximity of key individuals. With an increase in hereditary traits hoards and their significance in well-being insurance, the U.S. is the best market for human innate characteristics.

The increasing unavoidability of numerous endless inherent pollutions and growing governmental backing for cutting-edge work strategies are what are driving the European market for human genetic characteristics. The development is tended to in Germany, the best market, by the increased attention being paid to research practises by real market players in the areas of innate features and creative advancement.

The market in Asia Pacific is stimulated by the growing interest in studying inborn defects and the unsurprising rise in the extraordinary severity of genetic diseases. China, Japan, and India are the main countries contributing to the market improvement because of the increased accessibility of research working settings and the proximity of skilled workers, such as research trained professionals and others.

In the market for general human genetic characteristics, the Middle East and Africa make insignificant claims, but they do show steady progress when you take into account the growing funding for social assurance organisations and research projects, the poor financial situation, and the slower improvement in supportive working environments, especially in Africa.

Related Societies

Europe

• Clinical Epigenetics Society
• The Epigenetics Society
• Association of Clinical Cytogeneticists
• British Society for Human Genetics
• Clinical Genetics Society
• Clinical Molecular Genetics Society
• Genetics Society
• Human Genetics Commission
• Austrian Society for Human Genetics
• Belgian Society for Human Genetics
• Czech Society of Medical Genetics
• Danish Society of Medical Genetics
• Dutch Association of Clinical Genetics
• Finnish Society of Medical Genetics
• French Society of Human Genetics
• European Society for Medical Oncology
• European Oncology Nursing Society
• European Association for Cancer Research
• European Society of Human Genetics
• European Genetics Foundation
• European Cytogeneticist Association
• European Society of Gene Therapy
• Clinical Molecular Genetics Society

USA

• American Cancer Society
• Hematology/Oncology Pharmacy Association 
• American Association for Cancer Research 
• Association of International Cancer Research
• International Agency for Research on Cancer
• American Society of Human Genetics
• National Society of Genetic Counselors
• American College of Medical Genetics
• American Board of Genetic Counseling
• American Board of Medical Genetics
• Nation Coalition for Health Education in Genetics
• International Society of Nurses in Genetics
• Association of Genetic Technologists
• Genetic Society of America

 Asia and Middle East

• Australian Epigenetics Alliance
• Asian Clinical Oncology Society
• Asian Oncology Nursing Society
• Asian Society of Gynecologic Oncology 
• Asian Society for Neuro-Oncology
• East Asian Union of Human Genetics Societies
• Association of Chinese Geneticists in America
• Hong Kong Society of Medical Genetics
• Genetics Society of Korea
• Korean Society of Human Genetics
• Genetics Society of Vietnam
• Turkish Association of Medical Genetics
• Japan Society of Gene Therapy
• American Human Geneticists of Indian Subcontinent Origin
• Stem Cell Society of India

The 9th International Congress on Human Genetics and Genetic Disorders took place on July 8, 2022, webinar, with the participation of academic and professional researchers and practitioners working to develop high-quality education in all areas of human genetics expertise.

Conference Series played a key role in putting together a large panel of significant human genetics community members from research labs, industry, academia, and financial investing firms to discuss the future of human genetic specialisations. This gathering was planned to promote the development of concepts in the field of human genetics and the cross-fertilization of ideas. Examining the future directions of the actual genetic specialisations was its true objective.

On July 10–11, 2023, Dubai, United Arab Emirates will play home to the 11th International Conference on Human Genetics and Genetic Disorders. Conference series would like to express it’s sincere appreciation to the organisers of the conference, as well as to the numerous outside experts, business representatives, accomplished experts in their fields, and other notable people who worked with Conference series and provided the conference with unwavering support.