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Previous Speakers

Bharat Bhushan

Bharat Bhushan

Director The Ohio State University USA

Vittorio Colizzi

Vittorio Colizzi

Director of the UNESCO Chair of Biotechnology University of Rome Tor Vergata Italy

Fuad Fares

Fuad Fares

Professor,University of Haifa Israel Israel

Thomas McKeon

Thomas McKeon

Board Member International Society for Biocatalysis and Agricultural Biotechnology USA

George Perry

George Perry

Dean University of Texas USA

Lidietta Giorno

Lidietta Giorno

Director of the Institute on Membrane Technology National Research Council Italy Italy

Lucijan Mohorovic

Lucijan Mohorovic

Scientist University of Rijeka School of Medicine Croatia

Stefan Selbert

Stefan Selbert

Executive Director Business & Development PolyGene Transgenetics Switzerland

Human Genetics Meet 2019

About Conference - Human Genetics Meet 2019

Human Genetics Meet 2019 invites all the participants from all over the world to attend 6th World Congress on Human Genetics and Genetic Diseases during April 08-09, 2019, Abu Dhabi, UAE which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

Human Genetics is the field of biology which deals with the study of inheritance that occurs in the human and Diseases cause by any mutation or changes in the genes are termed as genetic diseases. Today gene editing can be used in various aspects to treat some of the genetic diseases.It also deals with the study of chromosomes and gene expression of an organism can give insight into heredity, genetic variation, and mutations.

 

Why to attend?

This International Conference provides a global platform to show case their research in the field of Human Genetics and Genetic Diseases which can be discussed through oral presentations, poster presentations, and workshops. Recent trending research like CRISPR gene and their role in cancer treatment could be discussed through this conference.  Scientist, Noble Laureate, researcher, research scholar, students and people together who are involved in the research can attend this conference to exchange their ideas and interact with each other.

Why Abu Dhabi?

Abu Dhabi is the capital city of United Arab Emirates and second most populous city after Dubai in the UAE. Most of the attractions of the city are tallest buildings, Historical moments, Ferrari World and so on.

Eastern Biotech in Abu Dhabi, is the first company in the Middle East to offer comprehensive genetic testing services. We have carefully examined the biotechnological horizon to identify the genetic tests most relevant to this region and offer them directly to the people of the Middle East.

ME Conferences selected UAE to conduct its conference on “Human Genetics and Genetics Diseases” so as to provide the global interaction and exchange their ideas via oral presentations, Poster presentation , Workshops and Symposia.

 

Target Audience

  • CEO of Genetic companies
  • Directors Of Genetic companies
  • Co-Directors of Genetic companies
  • Researchers
  • Scientists
  • Bioinformatician
  • Genetic engineers
  • Genetic counselors
  • Professors
  • Young Researchers 
  • Students
  • Technical Staff
  • Molecular biologists
  • Genetics Industries
  • Genetics Associations and Societies
  • Pharmaceutical companies

Sessions/Tracks for Human Genetics Meet 2019

Highlights of latest advances on Human Genetics Meet 2019

Track 01: Human Genetics

Human Genetics is the branch of genetics which involves the study of inheritance that occurs in humans. It includes various subfields such as classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics,population genetics, developmental genetics, clinical genetics, and genetic counseling. Study on human genetics , can explain the human nature, understand and development of effective treatment for diseases.

  • Genetic Differences and inheritance patterns

  • Genomics

  • Medical Genetics

  • Population Genetics

  • Mitochondrial DNA

  • Evolutionary Genetics

Track 02: Genomics

Genomics is the field of genetics which deals with the study of structure, function, evolution, mapping, and editing of genomes. Genomics involves the sequencing and analysis of genomes using  DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes.

Advancement in genomics made a transformation in discovery-based research and systems biology to  understand complex biological systems such as the brain.

Track 03: Genetic Diseases

Genetic Disorder may be caused as result of new mutation or changes that occur in DNA. It is also a hereditary diseases  that is caused from parents gene. Mostly it caused due to the abnormalities in the genome. Genetic disorders are classified into different types depending up on single gene or multiple genes. Around 4000 diseases are categorized as single gene defect. Some of the multifactorial  disorders include heart diseases and diabetes. Some of the common diseases are asthma, Diabetes, Hypertension and Obesity.

  • Diagnosis of genetic disorder

  • Prognosis of genetic disorder

  • Gene therapy

  • Inborn errors of metabolism

Some of the Common Genetic Disorders:

Track 04: Thalassemia

Thalassemia is characterized as an abnormal hemoglobin producing condition. It is a type of inherited blood disorders. Symptoms are mild to severe anemia due to low red blood cells count. Anemia can make one feel tired and have pale skin. Bone problems, an enlarged spleen, yellowish skin, dark urine, and among children slow growth are other related symptoms of Thalassemia.

There are two main types in thalassemia, alpha thalassemia and beta thalassemia. Diagnosis is done by blood tests including a complete blood count, special haemoglobin tests, and genetic tests. Diagnosis can also be done before birth by prenatal testing.

  • Signs and symptoms

  • Pathophysiology

  • Prevention

  • Management of thalassemia

Track 05:  Sickle cell Anaemia

Sickle-cell disease (SCD) is a group of blood disorders typically inherited from an individual’s parents. Amongst all, the most common type is known as sickle-cell anaemia (SCA). An abnormality in the oxygen-carrying protein haemoglobin (haemoglobin S) found in red blood cells is seen in SCD. This mainly leads to a rigid, sickle-like shape under certain circumstances. Sickel cell disease Problems typically begin around 5 to 6 months of age. Sickle-cell disease caused due to when inheritance two abnormal copies of the haemoglobin gene, one from each parent. This gene present in chromosome 11. Various subtypes exist, depending on the exact mutation in each haemoglobin gene. An attack can get started by temperature changes, stress, dehydration, and high altitude.

  • Signs and symptoms

  • Genetics of sickle Cell Anaemia

  • Pathophysiology of sickle-cell disease

  • Diagnosis of Sickle Cell Diseases

Track 06: Medical genetics

Medical genetics is a branch of medicine that involve diagnosis and management of genetic disorders. Slightly medical genetics and human genetics differ in certain ways, where human genetics is a field of scientific research which may or may not apply to medicine but medical genetics depend on the applications of  genetics to medical care.

  • Subspecialties - Clinical genetics, metabolic/biochemical genetics, Cytogenetics, Molecular genetics, Mitochondrial genetics

  • Genetic Counselling

  • Diagnostic evaluation- Chromosome studies, Basic metabolic studies, Molecular studies

  • Genetic Medicine- Gene therapy, Personalized medicine and Predictive medicine

Track 07: DNA sequencing

DNA sequencing is the process of determining the actual order of nucleotide (Adenine, Guanine, Cytosine, and thymine) with in a DNA molecule. This technique is used in various fields such as medical diagnosis, biotechnology, forensic biology, virology, and biological systematics and anthropology.

  • Basic methods - Maxam-Gilbert sequencing, Chain-termination methods

  • Advanced methods and de novo sequencing

  1. Shotgun sequencing
  2. Bridge PCR
  • High-throughput methods-

  1. Massively parallel signature sequencing (MPSS)
  2. Polony sequencing
  3. 454 pyrosequencing
  4. llumina (Solexa) sequencing
  5. SOLiD sequencing
  6. Ion Torrent semiconductor sequencing, DNA nanoball sequencing
  7. Heliscope single molecule sequencing
  8. Single molecule real time (SMRT) sequencing
  9. Nanopore DNA sequencing
  • Methods in development-

  1. Tunnelling currents DNA sequencing
  2. Sequencing by hybridization
  3. Sequencing with mass spectrometry
  4. Microfluidic Sanger sequencing
  5. Microscopy-based techniques
  6. RNAP sequencing
  7. In vitro virus high-throughput sequencing
  • Cancer Genome Sequencing

Track 08: Human Evolutionary genetics

Human evolutionary genetics explain how one human genome will differ from another human genome, from where the evolutionary past arrived that gave rise to it, and also its the current effects. This disparity between the genomes has anthropological, historical, medical and forensic implication and applications. Genetic data can provide important insight into human evolution. It helps one to understand the differences in the human genome and learn about how evolution has affected the development of the genome and acquired diversity.

  • Archaeogenetics

  • Human genetic variation

  • Race and genetics

  • FOXP2 and human evolution

  • Genetic genealogy

Track 09: Genome editing

It is a type of genetic engineering which involves addition, deletion, and insertion or modification of genome in an organism.  The Common thing in this research is to modify DNA sequence and observe the changes on the organism. This method is known as reverse genetics where it is vice versa to forward genetics in which the phenotype will be observed first and genetics of the organism will be studied later.

  • Site-directed mutagenesis

  • Gene therapy

  • Eradicating  diseases

  • Role of CRISPR in genome editing

Track 10: Cancer genetics

Cancer genetics studies about the heritable gene variants in humans and other animals that causes the change in risk of tumour or haematological malignancy.  An Individual cancer risk varies and is influenced by familial and sporadic oncogene or tumour suppressor gene mutations as well as rare and common constitutional variants present in the population. For many years, cancer genetics has mainly focused on mutational events which have their own primary effect within the cancer cell.

  • Cancer genomics

  • Cancer genome Sequencing

  • Cancer Epigenetics

  • Cancer Pharmacogenetics

  • Next generation sequencing in cancer

Track 11: Epigenetics

Epigenetics is a biological mechanism exhibiting functionally relevant changes to the genome that does not involve changes in the DNA sequences. Epigenetics controls the gene expression through the action of repressor protein that attaches to silencer regions of the DNA, switching between turn on and off of a gene, leading to alteration in the chromosomal regions.

  • Behavioral epigenetics

  • Computational Epigenetics

  • Nutriepigenomics

  • Epigenetic therapy

  • Epigenetics of neurodegenerative diseases

  • Epigenetic modifications in Cardiovascular disease

 

Track 12: Bioinformatics and Computational Biology

Bioinformatics is an interdisciplinary subject that develops methods and software tools for understanding concept of biological data. As an interdisciplinary field of science, bioinformatics is a combination of biology, computer science, mathematics and statistics to analyze and interpret the biological data. Using mathematical and statistical techniques, in silico analyses  of biological queries is carried out in Bioinformatics.

  • Novel bioinformatics/computational tools and methods

  • Computational epigenetics

  • Computational genomics

  • Cancer computational biology

  • Computational evolutionary biology

  • Computational Phylogenetics

  • Comparative genomics

Track 13: Pharmacogenomics and Pharmacogenetics

Pharmacogenomics is the study dealing with the response of an individual with respect to their genome to the administered drugs. As the name suggests it is the combination of two different fields that is pharmacology and genomics. Pharmacogenomics is often used interchangeably with pharmacogenetics. Adverse drug reactions are a significant cause of hospitalizations and deaths in many countries.

Track 14: Immunogenetics

Immunogenetics is under a division of medical genetics that exploits the relationship between the genetics and the immune system. Type 1 diabetes is an Autoimmune disease, it has complex genetic traits which result due to defects in the immune system. New target genes for therapeutic approaches are identified by Identification of genes defining the immune defects. Alternatively, by making use of genetic variation the immunological pathway leading to disease is defined. It highlights the emerging technical and various conceptual breakthroughs that pitch for mechanisms of anti-donor responses.

  • The immunogenetics of Neurological Disease

  • Immune-suppressive effects of interleukin-6

  • Bone involvement in monogenic autoinflammatory syndromes

  • Immunoglobulin genotypes and cognitive functions

  • Mechanisms behind TB, HBV, and HIV chronic infections

Track 15:  Stem cell therapy

Use of Stem cells for the treatment and prevention of diseased condition is categorized under stem cell therapy. Bone marrow transplant is found to be most widely used among various stem-cell therapies. Some stem cell therapies were acquired by using umbilical cord blood. Stem-cell therapy has turned into a controversial trailing to the developments where scientists are able to isolate and culture embryonic stem cells, to create stem cells using somatic cell nuclear transfer and their use of techniques to create induced pluripotent stem cells. These controversies often comprehend abortion politics and to human cloning. Stem cell therapy has been exploited for treatments of neurodegenerative diseases and conditions such as diabetes and heart disease.

Track 16:  Gene Mutation

A gene mutation happens due to permanent alteration in the DNA sequence that makes up a gene, in a way that the sequence differs from what is found in most of the normal individual. Mutations range in size; they can affect anywhere from a single DNA base pair to a large segment of a chromosome, one including multiple genes. It can be classified in two major ways that is hereditary mutations and acquired mutation.

  • Site-directed mutagenesis

  • Induced Mutations

  • Next generation panel sequencing

  • autoinflammatory disease genes in gene mutation

Track 17: Behavioural genetics

Behavioural genetics is the branch of genetics which deals with the study of behaviour of an organism. It also differentiates behaviour of different organism depending up on the genetics. Behavioural genetic studies have extensively impacted cutting-edge know-how the role of genetic and environmental impacts on behaviour. Different methodology involved are Animal studies, Twin and family studies, Quasi-experimental designs.

  • Evolutionary psychology

  • Genes, Brain and Behavior

  • Human behaviour genetics

  • Psychiatric genetics

  • Quantitative genetics

Track 18:  Neurogenetics

Neurogenetics is the branch of genetics which studies the development and function of nervous system. Many neurological disorders like Alzheimer’s  and  Parkinson’s  diseases can be related to neurogenetics and  the research of genetics on neurological disorder are still on going.

  • Neurological disorders- Alzeihmer's disease and Parkinson's disease

  • Gene sequencing

  • Methods of research

  • Behavioral neurogenetics

  • Current research

Track 19:  Genetic Counseling

Genetic counseling is the technique by which the patients or family liable to an inherited disease are counselled of the results and nature of the sickness, the possibility of growing or transmitting it, and the options open to them in management and family planning. This complicated procedure may be separated into diagnostic (the real estimation of threat) and supportive factors.

  • Genetic counsellors

  • Whole genome sequencing

  • Reprogenetics

  • Genomic counseling

Track 20: Nutrigenomics

Nutrigenomics is a department of nutritional genomics and is the study of the consequences of ingredients and food parts on gene expression. It is a area of research focusing on figuring out and knowledge molecular-level interaction between vitamins and different nutritional bioactives with the genome.

  • Background and preventive health

  • Anti-aging

  • Public health genomics

Track 21:  Regenerative medicine

Regenerative medication is the department of translational studies which involves the method of replacing, engineering or regenerating human cells, tissues or organs to restore or set up regular function. This area holds the promise of engineering broken tissues and organs via stimulating the frame's very own restore mechanisms to functionally heal formerly irreparable tissues or organs

  • Anti-aging medicine

  • Regeneration in humans

  • Biomedicine

  • Stem cell treatments

 


 

Market Analysis of Human Genetics Meet 2019

Today’s Market Study of Human Genetics in USA| Europe | Middle East | Asia Pacific

Asia Pacific: The global gene expression analysis market is projected to reach USD 7.30 Billion by 2022 from USD 3.39 Billion in 2015, at a CAGR of 9.3% from 2015 to 2022. The primary growth engine in this region is China, which is expected to register a growth rate of 15.2% in the forecast period.

USA:  The USA Genetics market is poised to reach USD 20.99 Billion by 2022, growing at a CAGR of 10.9% during the forecast period of 2015 to 2022.

Europe:  The Europe genetic market is estimated at USD 4.23 billion in 2018, and is projected to reach USD 6.8 billion by 2022, increasing with a compound annual growth rate (CAGR) of 11.2% during the forecast period, 2016-2022.

Middle East:  Market value of genetic companies around the globe was estimated $800in 2018 million in 2018 and it is estimated to be increased by 20% in the next 5 years.

Market Analysis

The global market for Genetic Testing is forecast to reach US$ 4.4 billion by 2020.

The regional analysis includes North America, Europe, Asia Pacific, Middle East and rest of the world.

The global human genetic market expected to grow with a CAGR of more than 10% in the upcoming years. The rise of growth rate is due to increase in technological advancement and various measures taken by US government to expand the national DNA databases.

The Duchene Muscular Dystrophy (DMD) treatment market is expected to change radically by 2020 in the six major pharmaceutical markets

A large number of DMD patients are not expected to be eligible for these promising new drugs, leaving vast opportunity for developers to deliver new therapies and for continued growth in the DMD market beyond 2020.

USA: Approximately, more than 24292 members involved in Genetics and related researches.

Europe: Approximately, more than 56083 members involved in Genetics and related researches.

Global: Approximately, 1292130 members involved in Genetics and related researches.

Behaviour and decision-making related to genetics and molecular biology, biotechnology, pharmaceuticals, medicals and academia.

Conference on Human Genetics basically deals with the latest research and developments in the topic of genetics and molecular biology. This Conference is providing a perfect platform for all the leading Research Scholars, and Scientists who achieved eminence in their field of study, research academicians from the universities and research institutions, industrial research professionals and business associates along with PhD Students to participate in this event  and Share their knowledge about the latest scientific advancements on this topic.

ME Conferences welcomes you to attend the 6th World Congress on Human Genetics and Genetic Diseases during April 08-10, 2019 Abu Dhabi, UAE. Human Genetics Meet 2019 inviting all the participants to share their knowledge and research in the area of Human Genetics and Genetic Diseases.

 

 

Related Conferences:

Human Genetics Confernces| Genetic Diseases Congress | Genomics Meetings| Medical Genetics  Events

1.        International Conference on  Molecular Biology and Medicine August 27-28, 2018 Dubai, UAE

2.        Cancer Genomics Conference October 08-09, 2018 Dubai, UAE

3.       10th Tissue Repair and Regeneration Congress December 10-11, 2018 Dubai, UAE

4.       5th World Congress on Epigenetics and Chromosome November 15-16, 2018 Istanbul, Turkey

5.       3rd Annual Aging Conference: Cellular Mechanisms and Therapeutics August 13-14, 2018 Dubai, UAE

6.       International Epigenetics and Epitranscriptomics Conference November 26-27, 2018 Helsinki,Finland

7.      4th International Congress on Epigenetics & Chromatin September 03-05, 2018 London, UK

8.       5th Annual Conference on Stroke and Neurological Disorders November 12-13, 2018 Istanbul, Turkey

9.       3rd World Conference on Breast and Cervical Cancer September 24-25, 2018 Abu Dhabi, UAE

10.   13th International Conference on Tissue Engineering & Regenerative Medicine July 12-13, 2018 , Paris, France

11.   10th Annual Conference on Stem Cell and Regenerative Medicine October 08-09, 2018 Zurich, Switzerland

12.   11th International Conference on Tissue Engineering & Regenerative Medicine October 18-20, 2018 Rome, Italy

13.   Annual congress on CRISPR-Cas9 Technology and Genetic Engineering October 24-25, 2018 Boston, USA

14.   2nd International Conference on Cancer Genetics and Epigenetics, May 24-25, 2018 Tokyo, Japan

15.   11th International Conference on Genomics and Pharmacogenomics  September 21-22, 2018 Philadelphia, USA

16.   World Congress on Stem Cell Biology and Biobanking September 3-4, 2018 Tokyo, Japan

17.   2nd Annual summit on Cell Signaling and Cancer Therapy September 19-20, 2018 Philadelphia, Pennsylvania, USA

18.   2nd Annual summit on Cell Metabolism and Cytopathology September 19-20, 2018 Philadelphia, Pennsylvania, USA

19.   28th World Congress on Neurology and Therapeutics February 28 – March 02, 2019 Berlin, Germany

20.    International Conference on Oncogenesis and Oncologic Emergency Medicine September 17-18, 2018 San Diego, California, USA

21.   Annual Congress on Cancer and Stem Cell Research October 17-18, 2018 New York, USA

22.   World Congress on Organ Transplantation and Artificial Organs August 24-25, 2018 Tokyo, Japan

23.   22nd International Chromosome conference 2 - 5 September 2018, Prague, Czech Republic

24.   4th International Conference on Synthetic Biology and Tissue Engineering October 18-19, 2018 Rome, Italy

25.   12th International Conference on Genomics and Molecular Biology April 15-17, 2019 Berlin, Germany

26.   9th International Conference and Exhibition on Advanced Cell and Gene Therapy March 21-22, 2019 Rome, Italy

 

Related Societies

Europe

1.   Clinical Epigenetics Society

2.   The Epigenetics Society

3.   Association of Clinical Cytogeneticists

4.   British Society for Human Genetics

5.    Clinical Genetics Society

6.    Clinical Molecular Genetics Society

7.    Genetics Society

8.    Human Genetics Commission

9.    Austrian Society for Human Genetics

10.   Belgian Society for Human Genetics

11.   Czech Society of Medical Genetics

12.   Danish Society of Medical Genetics

13.   Dutch Association of Clinical Genetics

14.   Finnish Society of Medical Genetics

15.   French Society of Human Genetics

16.   European Society for Medical Oncology

17.   European Oncology Nursing Society

18.   European Association for Cancer Research

19.   European Society of Human Genetics

20.   European Genetics Foundation

21.   European Cytogeneticist Association

22.   European Society of Gene Therapy

23.   Clinical Molecular Genetics Society

 

USA

1.   American Cancer Society

2.   Hematology/Oncology Pharmacy Association  

3.   American Association for Cancer Research  

4.   Association of International Cancer Research

5.   International Agency for Research on Cancer

6.   American Society of Human Genetics

7.    National Society of Genetic Counselors

8.   American College of Medical Genetics

9.   American Board of Genetic Counseling

10.  American Board of Medical Genetics

11.  Nation Coalition for Health Education in Genetics

12.  International Society of Nurses in Genetics

13.  Association of Genetic Technologists

14.  Genetic Society of America

 

Asia and Middle East

1.   Australian Epigenetics Alliance

2.   Asian Clinical Oncology Society

3.   Asian Oncology Nursing Society

4.   Asian Society of Gynecologic Oncology  

5.   Asian Society for Neuro-Oncology

6.   East Asian Union of Human Genetics Societies

7.   Association of Chinese Geneticists in America

8.   Hong Kong Society of Medical Genetics

9.   Japan Society of Human Genetics

10.  Genetics Society of Korea

11.  Korean Society of Human Genetics

12.  Genetics Society of Vietnam

13.  Turkish Association of Medical Genetics

14.  Japan Society of Gene Therapy

15.  American Human Geneticists of Indian Subcontinent Origin

16.  Stem Cell Society of India

New Updates:Human Genetics Meet 2019

Cystic hygroma

Introduction

A Cystic hygroma is a fluid filled sacs which occurs due to blockage in the Lymphatic system. It mostly occurs in neck and head area, but it can be found anywhere in the body. It may be found in a baby during a pregnancy ultrasound, or it may be clear at birth as a delicate bulge beneath the skin. Cystic hygromas influence 1 in 800 pregnancies and 1 in 8,000 live births. In 80% of cases, cystic hygromas show up on the face, counting the head, neck, mouth, cheek, or tongue. The growths may also occurs in other parts of the body; i.e. armpits, chest, legs, chest, buttocks and groin.

When it is distinguished on pregnancy ultrasound, there's an increased chance for miscarriage. In some cases, it isn't found until a person is older. Indications can change depending on its size and the particular area, and it can possibly cause issues with adjacent structures or organs.

Cystic hygromas usually influence children, but there have been uncommon cases of them showing up in adulthood.

Causes

The Cystic hygromas is caused due to environmental and genetic factors both. The exact cause of cystic hygromas isn't known but hereditary anomalies are present in around 25% to 75% of influenced children. The disease is more common in people with Turner syndrome, Down syndrome, or Klinefelter syndrome.

Symptoms

Symptoms may vary depending on the area of the cysts. A few children may not encounter any indications other than the growth.

If a child has symptoms, they may include:

·         fluid-filled sacs on the tongue

·         large cysts that appear blue

·         obstructive sleep apnea, a sleep disorder that causes breathing to stop and start

·         breathing and feeding difficulties

·         failure to thrive

·         bone and teeth abnormalities

In rare cases, the hygromas may bleed or become infected.

 

Designer baby

A designer baby is a genetically modified organism whose DNA sequencing has been altered using genetic engineering techniques. It is not a general way of Genetically Modified Organism or GMO which are used in the production of different types of medications, foods, and persuading scientific research. It is a great milestone in the field of human genetics. The designer baby which is made in vitro condition chooses the uncommon characteristics, which can change from lowered disease-risk to gender determination. The DNA sequence of the baby is altered by the addition of genetic material from an unrelated organism or deletion of a particular sequence.

With the growing research and technologies, scientists are developing new methods of genetic engineering and getting closer to being able to fiddle with the genes of a human embryo.

Designer babies represent an area inside embryology that has not ended up a practical reality till now, but in any case, draws out ethical concerns about whether or not it'll get to be fundamental to execute limitations regarding designer babies within the future.

Pros and Cons of Designer Babies

Advantages:

·         Reduces risk of genetic diseases

·         Reduces risk of inherited medical conditions

·         Keep pace with others doing it

·         Better chance the child will succeed in life

·         A better understanding of genetics

·         Increased life span

·         a completely new gene can be given to the child (non-hereditary)

·         Preventing the next generation from having any hereditary disease.

Disadvantages:

·         Termination of embryos

·         Could create a gap in society

·         The possibility of damage to the gene pool

·         Baby has no choice in the matter

·         Genes often have more than one use

·         Geneticists are not perfect

·         Loss of Individuality

·         Other children in the family could be affected by the parent's decision

·         Only the rich can afford it

 

Cancer epigenetics

Epigenetic mechanisms are fundamental for normal development and maintenance of tissue-specific gene expression patterns in warm-blooded animals. Disturbance of epigenetic processes can lead to altered gene work and dangerous cellular transformation. Worldwide changes within the epigenetic landscape are a trademark of cancer.

Epigenetic changes may be just as important, or indeed more critical, than hereditary mutations in a cell's transformation to cancer

The greatest conceptual breakthrough in the war on cancer was the acknowledgment by the 1980s that it is always a hereditary disease. Now and then the hereditary flaw is acquired. In some cases, it is the result of exposure to an exterior agent such as tobacco smoke or radioactivity. In some cases, it is plain bad luck; a miscopying of a piece of DNA during the typical prepare of cell division.

Metabolic recoding of epigenetics in cancer

Cancer-induced metabolic changes modify the epigenetic scene, particularly adjustments on histones and DNA, in this manner promoting harmful change, adjustment to lacking nutrition, and metastasis. The accumulation of certain metabolites in cancer can target epigenetic proteins to universally change the epigenetic landscape. Cancer-related metabolic changes lead to the locus-specific recoding of epigenetic marks.

The reversible nature of epigenetic variations has driven to the development of the promising field of epigenetic treatment, which is as of now making an advance with the later FDA endorsement of three epigenetic drugs for cancer treatment. In this survey, we examine the current understanding of changes within the epigenetic scene that occur in cancer compared with normal cells, the parts of these changes in cancer initiation and movement, counting the cancer stem cell model, and the potential utilizes of this information in planning more effective treatment procedures.

 
 
Unique Brain 'Fingerprint' Can Predict Drug Effectiveness

A unique "brain fingerprint" may offer assistance to distinguish the foremost useful therapeutic intervention for individual patients with neurologic clutter such as Alzheimer's disease,  possibly saving millions from experiencing ineffective treatment, modern research suggests. Investigators utilized computational brain modeling and artificial intelligence strategies to analyze positron emission tomography (PET) and MRI from over 300 patients with Alzheimer's Disease and healthy controls.

Thanks to technological advancement as that might change. From later discoveries, it is presently possible to think of personalized treatment for patients with certain neurological conditions. The concept capitalizes in reading the brain’s fingerprint. This tech can be utilized to better group patients with neurological illnesses so as to put them in line with the most successful therapeutic arrangements based on their particular needs.

The technique is called pTIF (personalized Therapeutic Intervention Fingerprint) and it rotates around anticipating the effectiveness of focusing on particular biological perspectives, such as brain amyloid/tau deposition, neuronal, functional dysregulation, and inflammation — with the sole expectation of managing how a patient’s disease evolves. This treatment option capitalizes on present-day innovations, artificial intelligence, and computational brain modeling.

The interesting portion is that usually the only study that has ever unmasked a direct connection between brain dynamics, molecular and cognitive alterations and predicted therapeutic reactions in patients. Meaning, specialists can presently utilize subtypes to plan drugs that do best with the specific patient, based on their phenotypic brain characteristics and their unique gene expression profile. Something the researchers expressed could be a major milestone in personalized medicine, and could immensely progress the effectiveness of treatment. Top on that this will cut the budget for clinical drug trials since researchers will be able to choose patients without guesswork.

Past Conference Report

Human Genetics Meet 2018

Human Genetics Meet  2018  Report

The 4th  World Congress on Human Genetics and  Genetic Diseases  was organized greatly, during April 19-20, 2018 at Dubai, UAE.

The conference was organized around the theme “New insights into the Genome Biology and Genetic Diseases.” which comprised of 16 Tracks designed to offer comprehensive sessions that address current issues in the field of human genetics and genetic diseases. This world congress conference brought eminent scientists together from all the nations and in which many critical issues were discussed in depth to provide up-to-date information to the world. On the other hand, the meeting provided a best platform for the young researchers to share their ideas and experiences.

The conference was greeted with a welcome message by our moderator Sylwia Bobis-Wozowicz, Jagiellonian University, Poland, Joel I Osorio, Westhill University, Mexico, Jiangwen Zhang, University of Hong Kong, Hong Kong, Namrata Londhe, Kokilaben Dhirubhai Ambani Hospital, India, Ghada Al-Kafaji, Arabian Gulf University, Bahrain,  Nabil Arrach , Progenesis Inc & University of California, USA and followed by oral presentations.

It’s really an honor to have the speakers from all over the world and it’s been a great moment to hear on different research papers at the time of oral presentations and also young research fellows has given a great talk about the current impacts on Human genetics. Finally, the program has been closed with panel discussion and certificate distribution.

We will get back to you all with Human Genetic Meet 2019, Initial Announcement and hope to see you all at our future conference.

For more details: http://humangenetics.geneticconferences.com/


Past Reports  Gallery  

To Collaborate Scientific Professionals around the World

Conference Date April 08-09, 2019

Speaker Opportunity

Supported By

Journal of Molecular and Genetic Medicine Journal of Pharmacogenomics & Pharmacoproteomics Journal of Human Genetics & Embryology Journal of Genetic Syndromes & Gene Therapy

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Keytopics

  • Agarose Gel Electrophoresis
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  • Behaviourial Genetics
  • Bioinformatics
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  • Biotechnology
  • Birth Congenital
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  • Cell
  • Cellular Biology
  • Cellular Biology
  • Chromosomal DNA
  • Clinical Genetics
  • Computational Biology
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  • Cytogenetics
  • DNA
  • DNA Fingerprinting
  • DNA Replication
  • Dominant Mutations And Genetic Disorders
  • Epidemology
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  • Evolutionary Genetics
  • Evolutionary Genetics
  • Forensic Biology
  • Gene Mutation
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  • Gene Mutation
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  • Gene Regulation
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  • Gene Sequencing
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  • Genes
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  • Genetic Diseases
  • Genetic Engineering
  • Genetic Hereditary
  • Genetic Linkage
  • Genetic Of Bone Biology
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  • Genetic Transmission
  • Genome
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  • Genomic Medicine
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  • Hematopoietic
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  • Syngeneic
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