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4th World Congress on Human Genetics and Genetic Diseases, will be organized around the theme “New insights into the Human Genetics and Genome Biology”

Human Genetics Meet 2018 is comprised of 16 tracks and 79 sessions designed to offer comprehensive sessions that address current issues in Human Genetics Meet 2018.

Submit your abstract to any of the mentioned tracks. All related abstracts are accepted.

Register now for the conference by choosing an appropriate package suitable to you.

Track 1: Human Genetics

Human genetics study is of inheritance as it occurs in human beings. Human geneticsencompasses varieties of overlapping fields including, genomicscytogeneticsmolecular genetics, classical genetics, biochemical genetics, population genetics, developmental genetics, clinical genetics, and genetic counseling. Genes can be the common factor of the qualities of most human-inherited traits.

  • Track 1-1Human Genome mapping
  • Track 1-2Human Genome sequencing
  • Track 1-3The genetics of human personality.
  • Track 1-4Medical Genetics
  • Track 1-5Human genetic clustering
  • Track 1-6Genetic differences and inheritance patterns
  • Track 1-7Spatial population genomics

Track 2: Genetic Diseases

Genetic diseases may be hereditary, passed down from the parents genes. In other genetic diseases, defects may be caused by new mutations or changes to the DNA. In that case, the defect will only be passed down if it occurs in the germ line. The same disease such as some forms of cancer may be caused by an inherited genetic condition in some people, by new mutations in other people, and mainly by the environmental causes in other people. A genetic disease is a genetic problem caused by one or more abnormalities in the genome, especially a condition that is present from birth congenital. Most genetic diseases are quite rare and affect one person in every several thousands or millions.

  • Track 2-1Gene therapy
  • Track 2-2Enzyme replacement therapy
  • Track 2-3Drug treatments
  • Track 2-4RNAi therapies
  • Track 2-5Treatment of Allergies and Autoimmune Diseases.

Sickle-cell disorder takes place when someone inherits two bizarre copies of the haemoglobin gene, one from each parent. This gene takes place in chromosome eleven. Several subtypes exist, relying on the exact mutation in every haemoglobin gene. An assault may be activate by using temperature modifications, strain, dehydration, and high altitude. A individual with a unmarried extraordinary reproduction does not commonly have symptoms and is stated to have sickle-cell trait.

  • Track 3-1Signs and symptoms
  • Track 3-2 Genetics
  • Track 3-3Pathophysiology of sickle-cell disease.
  • Track 3-4Diagnosis of Sickle Cell Diseases

Thalassemia is a genetic disorder  which is caused as a result of abnormal haemoglobin production. Thalassemia are genetic disease inherited from a person's dad and mom. There are  most important type, alpha thalassemia and beta thalassemia. The severity of alpha and beta thalassemia relies upon on how among the four genes for alpha globin or two genes for beta globin are lacking.

  • Track 4-1Signs and symptoms
  • Track 4-2Pathophysiology
  • Track 4-3Management of thalassemia

Track 5: Evolutionary genetics

Evolutionary genetics is the broad field of studies that resulted from the integration of geneticsand Darwinian evolution, called the modern synthesis. The force of mutation is the ultimate source of new genetic variation within populations. Although most mutations are neutral with no effect on fitness or harmful, some mutations have a small, positive effect on fitness and these variants are raw materials for gradualist adaptive evolution. Within finite populations, random genetic drift and natural selection affect the mutational variation. Natural selection is the only evolutionary force which can produce adaptation, the fit between organism and environment, or conserve genetic states over very long periods of time in the face of the dispersive forces of mutation and drift.

  • Track 5-1Mutation and polymorphism
  • Track 5-2Admixture and ancestry analysis
  • Track 5-3Natural selection and adaptation
  • Track 5-4Origin of life in a digital microcosm.
  • Track 5-5Genetic diversity and phylogenetic study of Humans

Track 6Molecular Biology 

Molecular biology is the study of molecular underpinnings of the processes of replication, transcriptiontranslation, and cell function. Molecular biology concerns the molecular basis of biological activity between the biomolecules in various systems of a cellgene sequencing and this includes the interactions between the DNA, RNA and proteins and their biosynthesis. In molecular biology the researchers use specific techniques native to molecular biology, increasingly combine these techniques and ideas from the genetics and biochemistry.

  • Track 6-1Macromolecule blotting and probing
  • Track 6-2Role of Molecular Biology in Cancer Treatment
  • Track 6-3Molecular cloning
  • Track 6-4Central dogma of molecular biology
  • Track 6-5Protein interaction prediction
  • Track 6-6Protein structure prediction

Track 7: Gene Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extra chromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA, which then may undergo error-prone repair or cause an error during other forms of repair, or else may cause an error during replication translation synthesis. Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics phenotype of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including functional diversity. The genomes of RNA viruses are based on RNA rather than DNA. The RNA viral genome can be double stranded DNA or single stranded. In some of these viruses such as the single stranded human immunodeficiency virus replication occurs quickly and there are no mechanisms to check the genome for accuracy.

  • Track 7-1Induced Mutations
  • Track 7-2Site-directed mutagenesis
  • Track 7-3Next generation panel sequencing
  • Track 7-4Are There Different Kinds of Aging?
  • Track 7-5autoinflammatory disease genes in gene mutation

Track 8Molecular Genetics

 Molecular genetics is the sector of biology that research the structure and characteristic of genes at a molecular stage and hence employs strategies of each molecular biology and genetics. The study of chromosomes and gene expression of an organism can give insight into heredity, genetic variant, and mutations. This is useful in the observe of developmental biology and in expertise and treating genetic illnesses.

  • Track 8-1DNA replication stress and cancer chemotherapy.
  • Track 8-2Gene therapy
  • Track 8-3The Human Genome Project
  • Track 8-4Viral Infection and Apoptosis.
  • Track 8-5Role of Non-Coding RNAs in the Etiology of Bladder Cancer.

Track 7: Bioinformatics

Bioinformatics is both an umbrella term for the body of biological studies that use computer programming as part of their methodology, as well as a reference to specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidate genes and single nucleotide polymorphisms. Often, such identification is made with the aim of better understanding the genetic disease, unique adaptations, and desirable properties in agricultural species, or differences between populations. In a less formal way, bioinformatics also tries to understand the organizational principles within nucleic acid and protein sequences, called proteomics.

  • Track 9-1Methods/tools for variant calling in human genomes
  • Track 9-2 Genome sequencing and assembly
  • Track 9-3Methods for data integration
  • Track 9-4Novel bioinformatics/computational tools and methods
  • Track 9-5Analysis of mutations in cancer
  • Track 9-6Computational biomodeling

Track 10: Molecular Modeling

Molecular modeling encompasses all methods, theoretical and computational, used to model or mimic the behavior of molecules. The methods are used in the fields of computational chemistry, drug design, computational biology and materials science to study molecular systems ranging from small chemical systems to large biological molecules and material assemblies. The simplest calculations can be performed by hand, but inevitably computers are required to perform molecular modeling of any reasonably sized system. The common feature of molecular modeling methods is the atomistic level description of the molecular systems.

  • Track 10-1Differential processing in modality-specific Mauthner cell dendrites.
  • Track 10-2Molecular docking
  • Track 10-3Molecular Modelling of Peptide-Based Materials for Biomedical Applications.
  • Track 10-4Cheminformatics
  • Track 10-5Formal Models of Biological Systems.

Track 11: Gene Sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. It includes any method or technology that is used to determine the order of the four bases is: adenine, guanine, cytosine, and thymine, in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, and in numerous applied fields such as medical diagnosis, biotechnologyforensic biology, virology and biological systematics. The rapid speed of sequencing attained with modern DNA sequencing technology has been instrumental in the sequencing of complete DNA sequences, or genomes of numerous types and species of life, including the human genome and other complete DNA sequences of many animal, plants, and microbial species.

  • Track 11-1Next-Generation Gene Sequencing
  • Track 11-2The impact of hereditary cancer gene panels on clinical care
  • Track 11-3gene and protein expression across multiple studies and organisms.
  • Track 11-4Evaluation of whole genome sequencing
  • Track 11-5Computational challenges of gene sequencing

Track 12: Pharmacogenetics

Pharmacogenetics is the study of germ line mutations, the single-nucleotide polymorphisms affecting genes coding for liver enzymes responsible for drug deposition and pharmacokinetics, whereas pharmacogenomics refers to somatic mutations in tumoral DNAleading to alteration in drug response KRAS mutations in patients treated with anti-Her1 biologics. Pharmacogenetics is an inherited genetic difference in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects. The term Pharmacogenetics is often used interchangeably with the term pharmacogenomics which also investigates the role of acquired and inherited geneticdifferences in relation to drug response and drug behavior through a systematic examination of genes, gene products, and inter- and intra-individual variation in gene expression and function

  • Track 12-1Functional studies of associated variants or loci
  • Track 12-2Genome-wide association studies
  • Track 12-3Candidate genes/regions and fine mapping
  • Track 12-4Clinical Pharmacogenetics
  • Track 12-5pharmacogenetics and drug-drug interactions.
  • Track 12-6Pharmacogenetics in Cardiovascular Medicine.
  • Track 12-7Pharmacoepigenetics and Toxicoepigenetics

Track 13Immunogenetics

Immunogenetics is the branch of medical research that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease.

  • Track 13-1The immunogenetics of Neurological Disease.
  • Track 13-2Immune-suppressive effects of interleukin-6
  • Track 13-3Bone involvement in monogenic autoinflammatory syndromes.
  • Track 13-4Immunoglobulin genotypes and cognitive functions
  • Track 13-5Mechanisms behind TB, HBV, and HIV chronic infections.

Track 14Epigenetics

Epigenetics are stable heritable traits that cannot be explained by changes in DNA sequence. Epigenetics often refers to changes in a chromosome that affect gene activity and expression, but can also be used to describe any heritable phenotypic change that does not derive from a modification of the genome, such as prions. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal developmental program. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA. These epigenetic changes may last through cell divisions for the duration of the cell's life, and may also last for multiple generations even though they do not involve changes in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism's genes to behave or "express themselves" differently.

  • Track 14-1Structure and Epigenetic Regulation of Chromatin Fibers.
  • Track 14-2DNA methylation
  • Track 14-3X-inactivation
  • Track 14-4Histone modification
  • Track 14-5Basics of Epigenetic Control.-Primer in Genetics and Genomics

 Track 15Translational Medicine

Translational medicine is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative; "bench-to-bedside" approach. Within public health, translational medicine is focused on ensuring that proven strategies for disease treatment and prevention are actually implemented within the community. One prevalent description of translational medicine, first introduced by the Institute of Medicine's Clinical Research Roundtable, highlights two roadblocks that is distinct areas in need of improvement the first translational block (T1) prevents basic research findings from being tested in a clinical setting; the second translational block (T2) prevents proven interventions from becoming standard practice. The National Center for Advancing Translational Science (NCATS) was established within the NIH to "transform the translational science process so that new treatments and cures for disease can be delivered to patients faster.

  • Track 15-1Xenotransplantation.
  • Track 15-2Allogeneic hematopoietic cell transplantation
  • Track 15-3Translational Genomics

Track 16Stem cell Transplantation

Hematopoietic stem cell transplantation  is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. It may be autologous the patient's own stem cells are used, allogeneic the stem cells come from a donor or syngeneic from an identical twin. It is a medical procedure in the field of hematology, most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic .

Hematopoietic stem cell transplantation remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer, such as autoimmune diseases and hereditary skeletal dysplasia’s notably malignant infantile osteoporosis and mucopolysaccharidosis.

  • Track 16-1What is the role of apheresis technology in stem cell transplantation
  • Track 16-2Linking Race, Cancer Outcomes and Tissue Repair.
  • Track 16-3Expanding transplantation of patients with a liver cancer without harming allocation